Ember Cube 2 Connected Cold Chain Shipper

Ember LifeSciences, Inc. launched as an offshoot of Ember Technologies' design-led temperature control brand Ember, founded by inventor Clay Alexander, and has its global headquarters in Westlake Village, California. It applies Ember's temperature control know-how to the transport of medicines and vaccines, where single-use packaging, temperature excursions and limited visibility cause waste and spoilage.

Ember Cube 2 is a reusable, modular cellular-connected shipping box with a vacuum-insulated payload compartment and phase change material packs that keep payloads between 2 °C and 8 °C for 72+ hours. It tracks GPS location, payload and ambient temperature and humidity in real time, and a cloud dashboard shows the whole fleet of cubes with alerts for low remaining cold storage energy, shipping delays and lid openings. Proprietary software generates digital shipping labels. Users include pharmaceutical distributors, pharmacies, hospitals and patients receiving medicines.

• Vacuum-insulated payload: thermal design holding 2-8 °C for 72+ hours.
• Phase change material packs: reusable cold storage packs replacing single-use refrigerants.
• Real-time tracking: GPS location, payload temperature, ambient temperature and humidity over cellular.
• Fleet dashboard: view all cubes and drill down to each shipment's status.
• Custom alerts: low cold storage energy, shipping delays, lid openings and user-defined events.
• Digital labeling: on-box shipping labels generated by Ember software.

• A pharmacy chain in Vietnam can deliver vaccines and insulin from central warehouses to stores in reusable connected cubes.
• A pharmaceutical distributor can ship high-value biologics to hospitals with lid-opening and temperature alerts.
• A clinical trial service can send temperature-sensitive drugs directly to patients' homes with chain of custody records.

• Payloads stay between 2 °C and 8 °C for 72+ hours with real-time temperature and GPS visibility.
• Cubes are reusable hundreds of times, and the product page states that the cube lowers CO2 emissions by 92% and reduces reliance on single-use packaging.
• Alerts on lid openings, delays and low cold storage energy support chain of custody and early intervention.
• Digital labels generated by the software reduce printed label waste and manual handling.

Pharmaceutical distribution is shifting toward reusable, connected shippers as specialty drugs, home delivery and sustainability targets grow, and as regulators expect electronic temperature records. In Vietnam, the expansion of pharmacy chains and home medicine delivery raises demand for last-mile cold chain packaging with verifiable temperature data.

Ember LifeSciences, Inc. is headquartered in Westlake Village, California, with Clay Alexander as Founder and Chairman. Its Series A reached 27 million USD in May 2026, led by Sea Court Capital with Amgen Ventures and TDF Ventures joining. The original Ember Cube was a 2024 TIME Invention of the Year, and the company announced a capital and business alliance with Alfresa for Japan's pharmaceutical cold chain.