HeartFlow

HeartFlow is a US medical technology company headquartered in San Francisco, California. It addresses a gap in standard coronary CT angiography reporting, which typically describes plaque only qualitatively and often cannot show whether a blockage actually restricts blood flow, leading to unnecessary invasive tests or delayed treatment for coronary artery disease.

The HeartFlow One platform turns a patient’s coronary CT scan into a personalized 3D model of the heart and applies computational analysis to assess both anatomy and blood-flow physiology. Its modules include Roadmap Analysis for disease detection, FFRCT Analysis for flow assessment, Plaque Analysis and Plaque Staging for risk stratification, and PCI Navigator for intervention planning. Customers are hospitals and cardiologists; the company reports use at more than 1,800 institutions and over 650,000 patients treated to date.

1. Roadmap Analysis: reads coronary CT scans to detect coronary artery disease.

2. FFRCT Analysis: estimates blood flow to judge whether a blockage needs treatment.

3. Plaque Analysis: quantifies and characterizes coronary plaque from CT imaging.

4. Plaque Staging: classifies patients into a standardized disease-severity framework.

5. PCI Navigator: supports planning for percutaneous coronary intervention.

6. Institutional reach: used by more than 1,800 hospitals and cardiology practices.